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Download and install Firefox.
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Download and install the "CLC-4-TTS Suite with CLiCk, Speak - Bundle Pack" from the downloads page.
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Start Firefox and go to File, Open File. Then choose the file you just downloaded in the previous step.
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Click the "Install Now" button on the window that pops up.
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Go to "Tools", "CLiCk, Speak Options" and select "Mac TTS". Congratulations, you've just set up CLiCk, Speak. If you don't hear any speech, try exiting Firefox and repeating this last step again.